Features

This system is especially suitable for Western blotting analysis. The high sensitive chemiluminescent detection system is designed to replace x-ray film. A wide variety of excitation light sources enables this system to capture various fluorescent images, including in vivo imaging or fluorescent Western blotting. In addition, the image acquisition and digitize option can capture both chemiluminescence and visible markers with one click.

New Super CCD Area Type Imaging Chip - The higher sensitivity of Fujifilm's new CCD provides improved faint-light image capture with outstanding image clarity. The new chip contains 3.2M pixels of which 3.15M contribute to actual imaging. The increased pixel size results from the use of octagonal-shaped photodiodes, which capture a great deal of light. The superior image sensing capability of the new chip results in ultra-high resolution image files of up to 6.3M pixels (3,072 x 2,048 pixels).

Super CCD - By rotating pixels 45 degrees to form an interwoven layout, the Super CCD's pixel pitch in the horizontal and vertical directions is narrower than in the diagonal direction, achieving higher horizontal and vertical resolution. The resulting interpolating algorithm produces a conventional interline raster image with higher resolution and image size than the CCD pixel count would indicate.

Conventional CCD - With conventional interline CCDs, pixel pitch in the diagonal direction is narrower than in the horizontal and vertical directions, resulting in higher diagonal resolution. Most conventional CCDs are of this type and even though they also apply algorithms to "enhance" the resolution, they fundamentally cannot improve on the resolution provided by the inherent vertical and horizontal CCD spacing.

New Binning Mode - The LAS-4000 features a new binning mode, which allows users to effectively increase the pixel size and, therefore, the imaging sensitivity of the system. Additionally, the process significantly enhances the signal-to-noise ratio. The system allows four binning settings: 1x2 (standard), 2x4 (high), 4x8 (super) and 8x16 (ultra). Images obtained in the binning mode are further enhanced by software-based pixel supplement to compensate for any loss in resolution. The binning mode of the LAS-4000 allows researchers to select from four binning settings to enhance both imaging sensitivity and image resolution. With the Image Reader Pro software, High resolution, High binning, Super binning and Ultra binning images can be obtained in addition to the standard High, Super and Ultra images.

Exposure Options - The extremely fast, electronically cooled, high-resolution camera component allows long exposure times in any laboratory setting. Exposures can be set from 1/100th of a second to 30 hours to meet a wide range of imaging conditions. The 30-hours exposure function allows over-night exposures on very dark images.

New Filter Options - A 5-position filter turret is mounted in front of the lens, which allows convenient, electrically controlled filter selection in less than ten seconds. With Image Reader software, the user has control over three standard filters (605DF40 for EtBr, Y515 for SYBR® Green and 510DF10 for GFP), a fourth filter position for chemiluminescence and a fifth user-specified filter for fluorescence. With Image Reader software, the user has full control over four filter types and positions. Other than the above, 575DF20 filter was prepared for green LED, L41 filter was prepared for UV LED, and IR785 filter was prepared for IR LED.

Additional Light Sources - The number of light sources on the LAS-4000 system has been increased to eight, including UV transilluminator, white transilluminator, epi-blue illuminator, epi-green illuminator, epi-red illuminator, epi-UV illuminator, epi-IR illuminator, epi-white illuminator. With ImageReader software, the user has control over eight light sources (UV transilluminator, white transilluminator, epi-blue illuminator, epi-green illuminator, epi-red illuminator, epi-UV illuminator, epi-IR illuminator and epi-white illuminator).

Sampling Convenience - The LAS-4000 accommodates samples up to 25x25cm in size with an optional wide view lens. Various types of trays are prepared such as an EPI Tray for chemiluminescence and epi-illuminator, a DIA Tray for UV trans-illuminator , a white-DIA Tray for white trans-illuminator such as CBB stained gel, and a non-parallax (NP) Tray for up to two titer plates. The NP tray includes a Fresnel lens located between the titer plate and the lens, which eliminates parallax in each of the 96 titer plate wells. NP Tray is designed for the detection of chemiluminescence.